Systemic autoimmune diseases, anti-rheumatic therapies, COVID-19 infection risk and patient outcomes
نویسندگان
چکیده
منابع مشابه
Cancer Risk in Patients With Inflammatory Systemic Autoimmune Rheumatic Diseases
The aim of this study was to determine whether inflammation is related to cancer development, and whether the incidence of cancer is increased and occurs in a site-specific manner in patients with systemic autoimmune rheumatic diseases (SARDs).This study included a nationwide dynamic cohort of patients with various newly diagnosed SARDs from 1997 to 2010 with follow-up until 2012.This study inc...
متن کاملImmune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases
Autoimmune diseases encompass a wide range of organ-specific and systemic disorders with a complex etiology. An intricate interplay of genetic, environmental, as well as immunological factors leads to the development of these debilitating diseases. In the absence of infections, regulatory processes inhibit immune responses towards antigen. Moreover , the immune system has multiple levels of neg...
متن کاملImmune-Regulatory Mechanisms in Systemic Autoimmune and Rheumatic Diseases
Systemic autoimmune and rheumatic diseases (SAIRDs) are thought to develop due to the failure of autoimmune regulation and tolerance. Current therapies, such as biologics, have improved the clinical results of SAIRDs; however, they are not curative treatments. Recently, new discoveries have been made in immune tolerance and inflammation, such as tolerogenic dendritic cells, regulatory T and B c...
متن کاملPrevalence of anti-DFS70 antibodies in patients with and without systemic autoimmune rheumatic diseases.
OBJECTIVES Autoantibodies to the dense fine speckled 70 (DFS70) antigen are common among antinuclear antibodies (ANA) positive healthy individuals (HI). We assessed the prevalence of anti-DFS70 antibodies in patients with and without ANA-associated rheumatic diseases (AARDs) by two methods: chemiluminescent immunoassay (CIA) and an indirect immunofluorescence (IIF) assay based on immunoadsorpti...
متن کاملAutoimmune Rheumatic Diseases
1 Center for Autoimmune Diseases Research (CREA), Universidad del Rosario, Carrera 24 No. 63C-69, 111221 Bogota, Colombia 2 ZabludowitczCenter forAutoimmuneDiseases, ShebaMedical Center, Tel-Hashomer, Sackler Faculty ofMedicine, Tel AvivUniversity, 52621 Tel-Hashomer, Israel 3 Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Charitéplatz 1, 10117 Berlin, Germany 4...
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ژورنال
عنوان ژورنال: Rheumatology International
سال: 2020
ISSN: 0172-8172,1437-160X
DOI: 10.1007/s00296-020-04629-x